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Furthermore, creatine supplementation (1 g/kg BW per day for 21 days) to Walker-256 tumor-bearing rats prevented skeletal muscle atrophy by attenuating systemic inflammation and protein degradation signaling, thereby enhancing their muscle mass and survival (Cella et al

nausea, vomiting, diarrhoea, abdominal pain) are common across the class nausea is likely at initiation and decreases over time

Metabolomic profiling of tumor tissue from treated subjects showed dramatic alterations in cellular energy metabolism

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